Necessity of Blood Clotting
Blood clotting is necessary to prevent blood loss from the body when there is damage to the blood vessels. It prevents blood pressure from falling to a low level as pressure is needed to maintain proper blood circulation. A blood clot seals a wound and prevents the entry of microorganisms and foreign particles into the body through the wound.
Blood Clotting Mechanism
What happens when you accidentally cut your fingers and bleeding occurs? In your blood there are cells called the platelets which help in blood clotting. When you get a cut, the blood vessels around the wound immediately constrict to reduce blood loss. The platelets in the blood become sticky and clump together to plug the wound.
Clotting factors are released by the platelets and damaged tissues which set off a chain of reactions. Thrombokinase, in the presence of factor VIII, converts prothrombin into thrombin. The formation of prothrombin in the liver requires vitamin K. thrombin converts a soluble plasma protein, fibrinogen, into insoluble fibrin fibres which form a meshwork of threads over the wound. As the blood flows out, erythrocytes and platelets are trapped in the fibrin fibres and blood clot forms. It dries to form a scab which covers the wound. When the wound heals, new skin is formed and the scab peels or falls off.
Blood clotting is necessary to prevent blood loss from the body when there is damage to the blood vessels. It prevents blood pressure from falling to a low level as pressure is needed to maintain proper blood circulation. A blood clot seals a wound and prevents the entry of microorganisms and foreign particles into the body through the wound.
Blood Clotting Mechanism
What happens when you accidentally cut your fingers and bleeding occurs? In your blood there are cells called the platelets which help in blood clotting. When you get a cut, the blood vessels around the wound immediately constrict to reduce blood loss. The platelets in the blood become sticky and clump together to plug the wound.
Clotting factors are released by the platelets and damaged tissues which set off a chain of reactions. Thrombokinase, in the presence of factor VIII, converts prothrombin into thrombin. The formation of prothrombin in the liver requires vitamin K. thrombin converts a soluble plasma protein, fibrinogen, into insoluble fibrin fibres which form a meshwork of threads over the wound. As the blood flows out, erythrocytes and platelets are trapped in the fibrin fibres and blood clot forms. It dries to form a scab which covers the wound. When the wound heals, new skin is formed and the scab peels or falls off.
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